Krukenberg's Spindles

Sleep Spindles

The development of EEC sleep-spindles in prematurely-born and full-term infants was studied to test an hypothesized impact of experience (longer extrauterine existence) upon innate maturational factors (EEG development). The age of otiset of sleep spindles and achievement of mature spindle quality occurs approximately 4 weeks earlier in prematurely-born infants than in full-term infants. Sleep ...

mini spindles

We describe a new Drosophila gene, mini spindles (msps) identified in a cytological screen for mitotic mutant. Mutation in msps disrupts the structural integrity of the mitotic spindle, resulting in the formation of one or more small additional spindles in diploid cells. Nucleation of microtubules from centrosomes, metaphase alignment of chromosomes, or the focusing of spindle poles appears muc...

Emergence of synchronous EEG spindles from asynchronous MEG spindles.

Sleep spindles are bursts of rhythmic 10-15 Hz activity, lasting ∼0.5-2 s, that occur during Stage 2 sleep. They are coherent across multiple cortical and thalamic locations in animals, and across scalp EEG sites in humans, suggesting simultaneous generation across the cortical mantle. However, reports of MEG spindles occurring without EEG spindles, and vice versa, are inconsistent with synchro...

Stimulation of muscle spindles

Characterization of Sleep Spindles

Local Field Potential (LFP) measurements from sleep data is important in Neurological studies because experiments have shown a correlation between sleep and memory consolidation [1]. The most prominent of the coherent signals within LFP sleep data are spindles, which occur most often when a person is dozing off, durring Stage 2 of Non-Rapid-Eye-Movement (NREM) sleep [2]. Determining the specifi...